Adhesive Force Regulation and Mechanotransduction

Mechanical forces regulate diverse cellular functions, and integrin receptor-based adhesive complexes have emerged as central players in force transmission from the extracellular matrix (ECM) to the cytoskeleton and conversion of forces into biochemical signals.  Learn more

Mechanobiology Technologies for Induced Pluripotent Stem Cells

Generation of human induced pluripotent stem cells (hiPSCs) from somatic cells via transduction with the Yamanaka factors represents a highly promising strategy to produce auto- and allogenic cell sources for therapeutic strategies as well as novel models of human development and disease. Learn more

Cell-instructive Adhesive Materials for Regenerative Medicine

Cell-based therapies represent promising strategies for various regenerative medicine applications including myocardial infarcts, type 1 diabetes, neurological disorders, and non-healing bone defects. Learn more

Biomaterials for Imaging and Modulating Inflammation and Infection

Inflammatory responses to implanted biomedical devices severely limit the biological performance of various devices in millions of patients. Learn more