Publications

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.
Agarwal R, Johnson CT, Imhoff BR, Donlan RM, McCarty NA, García AJ.
Nat Biomed Eng. 2018 Nov;2(11):841-849. doi: 10.1038/s41551-018-0263-5. Epub 2018 Jul 16. No abstract available.


Engineered materials to model human intestinal development and cancer using organoids.
Cruz-Acuña R, García AJ.
Exp Cell Res. 2019 Apr 15;377(1-2):109-114. doi: 10.1016/j.yexcr.2019.02.017. Epub 2019 Feb 19. Review.


Evidence for Innate and Adaptive Immune Responses in a Cohort of Intractable Pediatric Epilepsy Surgery Patients.
Owens GC, Garcia AJ, Mochizuki AY, Chang JW, Reyes SD, Salamon N, Prins RM, Mathern GW, Fallah A.
Front Immunol. 2019 Jan 29;10:121. doi: 10.3389/fimmu.2019.00121. eCollection 2019.


Implantable antimicrobial biomaterials for local drug delivery in bone infection models.
Caplin JD, García AJ.
Acta Biomater. 2019 Jan 14. pii: S1742-7061(19)30035-2. doi: 10.1016/j.actbio.2019.01.015. [Epub ahead of print]


Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids.
Capeling MM, Czerwinski M, Huang S, Tsai YH, Wu A, Nagy MS, Juliar B, Sundaram N, Song Y, Han WM, Takayama S, Alsberg E, Garcia AJ, Helmrath M, Putnam AJ, Spence JR.
Stem Cell Reports. 2019 Feb 12;12(2):381-394. doi: 10.1016/j.stemcr.2018.12.001. Epub 2019 Jan 3.


Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus.
Khuu MA, Pagan CM, Nallamothu T, Hevner RF, Hodge RD, Ramirez JM, Garcia AJ 3rd.
J Neurosci. 2019 Feb 13;39(7):1320-1331. doi: 10.1523/JNEUROSCI.1359-18.2018. Epub 2018 Dec 26.


Recommendations on screening for breast cancer in women aged 40-74 years who are not at increased risk for breast cancer.
Klarenbach S, Sims-Jones N, Lewin G, Singh H, Thériault G, Tonelli M, Doull M, Courage S, Garcia AJ, Thombs BD; Canadian Task Force on Preventive Health Care.
CMAJ. 2018 Dec 10;190(49):E1441-E1451. doi: 10.1503/cmaj.180463. No abstract available.


An affinity-based approach to engineer laminin-presenting cell instructive microenvironments.
Barros D, Parreira P, Furtado J, Ferreira-da-Silva F, Conde-Sousa E, García AJ, Martins MCL, Amaral IF, Pêgo AP.
Biomaterials. 2019 Feb;192:601-611. doi: 10.1016/j.biomaterials.2018.10.039. Epub 2018 Dec 1.


Localized immune tolerance from FasL-functionalized PLG scaffolds.
Skoumal M, Woodward KB, Zhao H, Wang F, Yolcu ES, Pearson RM, Hughes KR, García AJ, Shea LD, Shirwan H.
Biomaterials. 2019 Feb;192:271-281. doi: 10.1016/j.biomaterials.2018.11.015. Epub 2018 Nov 13.


Synthetic poly(ethylene glycol)-based microfluidic islet encapsulation reduces graft volume for delivery to highly vascularized and retrievable transplant site.
Weaver JD, Headen DM, Coronel MM, Hunckler MD, Shirwan H, García AJ.
Am J Transplant. 2018 Oct 31. doi: 10.1111/ajt.15168. [Epub ahead of print]


Publisher Correction: PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.
Cruz-Acuña R, Quirós M, Huang S, Siuda D, Spence JR, Nusrat A, García AJ.
Nat Protoc. 2018 Oct 24. doi: 10.1038/s41596-018-0079-5. [Epub ahead of print]


Inhibition of TBK1/IKKε Promotes Regeneration of Pancreatic β-cells.
Xu J, Jia YF, Tapadar S, Weaver JD, Raji IO, Pithadia DJ, Javeed N, García AJ, Choi DS, Matveyenko AV, Oyelere AK, Shin CH.
Sci Rep. 2018 Oct 22;8(1):15587. doi: 10.1038/s41598-018-33875-0.


2019 Canadian Guideline for Physical Activity Throughout Pregnancy: Methodology.
Davenport MH, Ruchat SM, Mottola MF, Davies GA, Poitras VJ, Gray CE, Garcia AJ, Barrowman N, Adamo KB, Duggan M, Barakat R, Chilibeck P, Fleming K, Forte M, Korolnek J, Nagpal T, Slater LG, Stirling D, Zehr L.
J Obstet Gynaecol Can. 2018 Nov;40(11):1468-1483. doi: 10.1016/j.jogc.2018.09.004. Epub 2018 Oct 18. No abstract available.


Between-year vocal aging in female red deer (Cervus elaphus).
Volodin IA, Sibiryakova OV, Vasilieva NA, Volodina EV, Matrosova VA, Garcia AJ, Pérez-Barbería FJ, Gallego L, Landete-Castillejos T.
BMC Res Notes. 2018 Oct 17;11(1):737. doi: 10.1186/s13104-018-3833-4.


Bacteria-Based Materials for Stem Cell Engineering.
Hay JJ, Rodrigo-Navarro A, Petaroudi M, Bryksin AV, García AJ, Barker TH, Dalby MJ, Salmeron-Sanchez M.
Adv Mater. 2018 Oct;30(43):e1804310. doi: 10.1002/adma.201804310. Epub 2018 Sep 12.


PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery.
Cruz-Acuña R, Quirós M, Huang S, Siuda D, Spence JR, Nusrat A, García AJ.
Nat Protoc. 2018 Sep;13(9):2102-2119. doi: 10.1038/s41596-018-0036-3. Erratum in: Nat Protoc. 2018 Oct 24;:.


Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma.
Han WM, Anderson SE, Mohiuddin M, Barros D, Nakhai SA, Shin E, Amaral IF, Pêgo AP, García AJ, Jang YC.
Sci Adv. 2018 Aug 15;4(8):eaar4008. doi: 10.1126/sciadv.aar4008. eCollection 2018 Aug.


A Minimally Invasive, Translational Method to Deliver Hydrogels to the Heart Through the Pericardial Space.
Garcia JR, Campbell PF, Kumar G, Langberg JJ, Cesar L, Wang L, García AJ, Levit RD.
JACC Basic Transl Sci. 2017 Oct 4;2(5):601-609. doi: 10.1016/j.jacbts.2017.06.003. eCollection 2017 Oct.


Early post-procedural patients compliance and VAS after UAE through transradial versus transfemoral approach: preliminary results.
Basile A, Rebonato A, Failla G, Caltabiano G, Boncoraglio A, Gozzo C, Motta A, Foti PV, Palmucci S, García AJ, Garcia-Medina J.
Radiol Med. 2018 Nov;123(11):885-889. doi: 10.1007/s11547-018-0920-5. Epub 2018 Jul 17.


Recommendations on screening for asymptomatic bacteriuria in pregnancy.
Moore A, Doull M, Grad R, Groulx S, Pottie K, Tonelli M, Courage S, Garcia AJ, Thombs BD; Canadian Task Force on Preventive Health Care.
CMAJ. 2018 Jul 9;190(27):E823-E830. doi: 10.1503/cmaj.171325. No abstract available.


Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis.
Enemchukwu NO, Cruz-Acuña R, Bongiorno T, Johnson CT, García JR, Sulchek T, García AJ. J Cell Biol. 2016 Jan 4


Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials.
Lee TT, García JR, Paez JI, Singh A, Phelps EA, Weis S, Shafiq Z, Shekaran A, Del Campo A, García AJ. Nat Mater. 2015 Mar


Simple coating with fibronectin fragment enhances stainless steel screw osseointegration in healthy and osteoporotic rats.
Agarwal R, González-García C, Torstrick B, Guldberg RE, Salmerón-Sánchez M, García AJ.
Biomaterials. 2015 Sep;63:137-45. doi: 10.1016/j.biomaterials.2015.06.025. Epub 2015 Jun 15.
PMID: 26100343


Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes.
Gutowski SM, Shoemaker JT, Templeman KL, Wei Y, Latour RA Jr, Bellamkonda RV, LaPlaca MC, García AJ.
Biomaterials. 2015 Mar;44:55-70. doi: 10.1016/j.biomaterials.2014.12.009. Epub 2015 Jan 12.
PMID: 25617126


Nanoengineered particles for enhanced intra-articular retention and delivery of proteins.
Singh A, Agarwal R, Diaz-Ruiz CA, Willett NJ, Wang P, Lee LA, Wang Q, Guldberg RE, García AJ.
Adv Healthc Mater. 2014 Oct;3(10):1562-7, 1525. doi: 10.1002/adhm.201400051. Epub 2014 Mar 31.
PMID: 24687997


Bone regeneration using an alpha 2 beta 1 integrin-specific hydrogel as a BMP-2 delivery vehicle.
Shekaran A, García JR, Clark AY, Kavanaugh TE, Lin AS, Guldberg RE, García AJ.
Biomaterials. 2014 Jul;35(21):5453-61. doi: 10.1016/j.biomaterials.2014.03.055. Epub 2014 Apr 13.
PMID: 24726536


How vinculin regulates force transmission.
Dumbauld DW, Lee TT, Singh A, Scrimgeour J, Gersbach CA, Zamir EA, Fu J, Chen CS, Curtis JE, Craig SW, García AJ.
Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9788-93. doi: 10.1073/pnas.1216209110. Epub 2013 May 28.
PMID: 23716647


Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes.
Phelps EA, Headen DM, Taylor WR, Thulé PM, García AJ.
Biomaterials. 2013 Jun;34(19):4602-11. doi: 10.1016/j.biomaterials.2013.03.012. Epub 2013 Mar 26.
PMID: 23541111


Adhesion strength-based, label-free isolation of human pluripotent stem cells.
Singh A, Suri S, Lee T, Chilton JM, Cooke MT, Chen W, Fu J, Stice SL, Lu H, McDevitt TC, García AJ.
Nat Methods. 2013 May;10(5):438-44. doi: 10.1038/nmeth.2437. Epub 2013 Apr 7. PMID: 23563795


Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery.
Phelps EA, Enemchukwu NO, Fiore VF, Sy JC, Murthy N, Sulchek TA, Barker TH, García AJ.
Adv Mater. 2012 Jan 3;24(1):64-70, 2. doi: 10.1002/adma.201103574. Epub 2011 Dec 16. No abstract available.
PMID: 22174081


Multivalent integrin-specific ligands enhance tissue healing and biomaterial integration.
Petrie TA, Raynor JE, Dumbauld DW, Lee TT, Jagtap S, Templeman KL, Collard DM, García AJ.
Sci Transl Med. 2010 Aug 18;2(45):45ra60. doi: 10.1126/scitranslmed.3001002.
PMID: 20720217


Bioartificial matrices for therapeutic vascularization.
Phelps EA, Landázuri N, Thulé PM, Taylor WR, García AJ.
Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3323-8. doi: 10.1073/pnas.0905447107. Epub 2009 Dec 31.
PMID: 20080569


Engineering graded tissue interfaces.
Phillips JE, Burns KL, Le Doux JM, Guldberg RE, García AJ.
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12170-5. doi: 10.1073/pnas.0801988105. Epub 2008 Aug 21.
PMID: 18719120


Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly.
Gallant ND, Michael KE, García AJ.
Mol Biol Cell. 2005 Sep;16(9):4329-40. Epub 2005 Jul 6.
PMID: 16000373


Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation.
Keselowsky BG, Collard DM, García AJ.
Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5953-7. Epub 2005 Apr 12.
PMID: 15827122